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MGST1 anticorps (N-Term)

Cet anticorps Lapin Polyclonal détecte spécifiquement MGST1 dans WB et IHC. Il présente une réactivité envers Humain, Souris et Rat.
N° du produit ABIN3042364

Aperçu rapide pour MGST1 anticorps (N-Term) (ABIN3042364)

Antigène

Voir toutes MGST1 Anticorps
MGST1 (Microsomal Glutathione S-Transferase 1 (MGST1))

Reactivité

  • 31
  • 6
  • 6
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Humain, Souris, Rat

Hôte

  • 32
  • 3
  • 1
Lapin

Clonalité

  • 31
  • 5
Polyclonal

Conjugué

  • 26
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp MGST1 est non-conjugé

Application

  • 24
  • 13
  • 7
  • 6
  • 6
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Épitope

    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 42-75, N-Term

    Fonction

    Anti-Microsomal Glutathione S-transferase 1/MGST1 Antibody Picoband®

    Séquence

    KVFANPEDCV AFGKGENAKK YLRTDDRVER VRRA

    Réactivité croisée (Details)

    No cross-reactivity with other proteins.

    Attributs du produit

    Anti-Microsomal Glutathione S-transferase 1/MGST1 Antibody Picoband® (ABIN3042364). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Purification

    Immunogen affinity purified.

    Immunogène

    A synthetic peptide corresponding to a sequence at the N-terminus of human MGST1, different from the related mouse sequence by six amino acids, and from the related rat sequence by five amino acids.

    Isotype

    IgG
  • Indications d'application

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry, 2-5 μg/mL, Human1. Lee SH, DeJong J (1999). "Microsomal GST-I: genomic organization, expression, and alternative splicing of the human gene.". Biochim. Biophys. Acta 1446 (3): 389-96. 2. "Entrez Gene: MGST1 microsomal glutathione S-transferase 1".

    Commentaires

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Concentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Antigène

    MGST1 (Microsomal Glutathione S-Transferase 1 (MGST1))

    Autre désignation

    MGST1

    Sujet

    Synonyms: Microsomal glutathione S-transferase 1,Microsomal GST-1,2.5.1.18,Microsomal GST-I,MGST1,GST12, MGST,

    Tissue Specificity: Highly expressed in liver.

    Background: Microsomal glutathione S-transferase 1 is an enzyme that in humans is encoded by the MGST1 gene. The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, two of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. Other family members, demonstrating glutathione S-transferase and peroxidase activities, are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. This gene encodes a protein that catalyzes the conjugation of glutathione to electrophiles and the reduction of lipid hydroperoxides. This protein is localized to the endoplasmic reticulum and outer mitochondrial membrane where it is thought to protect these membranes from oxidative stress. Several transcript variants, some non-protein coding and some protein coding, have been found for this gene.

    Poids moléculaire

    15 kDa

    ID gène

    4257

    UniProt

    P10620
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